Issue 61, 2019
From the journal:

Chemical Communications

Vehicle-saving theranostic probes based on hydrophobic iron oxide nanoclusters using doxorubicin as a phase transfer agent for MRI and chemotherapy†

Yanbing Cao,‡a   Juan Min,‡b   Dongye Zheng,c   Jiong Li,c   Yanan Xue,*a   Faquan Yu ORCID logo *a  and  Ming Wu ORCID logo *d  

* Corresponding authors

a Key Laboratory for Green Chemical Process of Ministry of Education, Hubei Key Laboratory for Novel Reactor and Green Chemistry Technology, Hubei Engineering Research Center for Advanced Fine Chemicals, and School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan 430205, P. R. China
E-mail: lina@sdnu.edu.cn, tangb@sdnu.edu.cn

b The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China
E-mail: wmmj0419@163.com

c Key Laboratory of Design and Assembly of Functional Nanostructures, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, P. R. China

d Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, P. R. China

Abstract

A simple approach for constructing theranostic nanobeads is developed by using doxorubicin as a phase transfer agent to solubilize small iron oxide nanoclusters. The nanobeads can be specifically internalized into cancer cells with the guidance of an external magnetic field, resulting in good MRI and chemotherapy.

Graphical abstract: Vehicle-saving theranostic probes based on hydrophobic iron oxide nanoclusters using doxorubicin as a phase transfer agent for MRI and chemotherapy

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Article information

DOI
https://doi.org/10.1039/C9CC03868J
Article type
Communication
Submitted
19 May 2019
Accepted
03 Jul 2019
First published
03 Jul 2019

Chem. Commun., 2019,55, 9015-9018

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Vehicle-saving theranostic probes based on hydrophobic iron oxide nanoclusters using doxorubicin as a phase transfer agent for MRI and chemotherapy

Y. Cao, J. Min, D. Zheng, J. Li, Y. Xue, F. Yu and M. Wu, Chem. Commun., 2019, 55, 9015 DOI: 10.1039/C9CC03868J

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