A FRET probe for the detection of alkylating agents†
Frédéric
Taran 
*a
and
Thierry
Le Gall
*a
*a
and
Thierry
Le Gall
*a
Abstract
Herein, we describe a new strategy for the detection of reactive alkylating agents such as alkyl halides. These toxic compounds react with a FRET-based profluorescent probe, triggering a self-immolative elimination at room temperature, thus leading to a fluorescence signal.
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