Issue 82, 2019

Nitrobenzyl-based fluorescent photocages for spatial and temporal control of signalling lipids in cells

Abstract

Here we present a set of fluorescent cages prepared by tethering fluorescent dyes to a photolabile group. The developed molecules enable caging of signalling lipids, their delivery to specific cellular membranes, with further imaging, quantification, and controlled photorelease of active lipids in living cells.

Graphical abstract: Nitrobenzyl-based fluorescent photocages for spatial and temporal control of signalling lipids in cells

Supplementary files

Article information

Article type
Communication
Submitted
19 Jul 2019
Accepted
27 Aug 2019
First published
16 Sep 2019
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2019,55, 12288-12291

Nitrobenzyl-based fluorescent photocages for spatial and temporal control of signalling lipids in cells

P. Gaur, O. A. Kucherak, Y. G. Ermakova, V. V. Shvadchak and D. A. Yushchenko, Chem. Commun., 2019, 55, 12288 DOI: 10.1039/C9CC05602E

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