Issue 7, 2019
From the journal:

CrystEngComm

Spontaneous single-crystal to single-crystal transition with self-healing cracks involving solvent exchange†

Jie Shen,‡ab   Hongzhen Bai, ORCID logo ‡a   Xinbo Zhou,a   Jiyong Liu,a   Xiurong Hu,a   Paul K. Chu*b  and  Guping Tang ORCID logo *ab  

* Corresponding authors

a Department of Chemistry, Zhenjiang University, Hangzhou 310028, China
E-mail: tangguping@zju.edu.cn

b Department of Physics and Department of Materials Science and Engineering, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China
E-mail: paul.chu@cityu.edu.hk

Abstract

Darunavir provides robust frameworks for single-crystal to single-crystal transformation (SCSCT). The SCSCT via solvent exchange to get a new single crystal of darunavir dihydrate is accompanied by a rare process of crystal breaking to self-healing. The transformation mechanism is unraveled at the molecular level.

Graphical abstract: Spontaneous single-crystal to single-crystal transition with self-healing cracks involving solvent exchange

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Article information

DOI
https://doi.org/10.1039/C8CE02110D
Article type
Communication
Submitted
14 Dec 2018
Accepted
17 Jan 2019
First published
01 Feb 2019

CrystEngComm, 2019,21, 1102-1106

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Spontaneous single-crystal to single-crystal transition with self-healing cracks involving solvent exchange

J. Shen, H. Bai, X. Zhou, J. Liu, X. Hu, P. K. Chu and G. Tang, CrystEngComm, 2019, 21, 1102 DOI: 10.1039/C8CE02110D

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