Visible-light-induced radical cyclization of N-allylbenzamides with CF3SO2Na to trifluoromethylated dihydroisoquinolinones in water at room temperature

Abstract

A green and efficient strategy for the preparation of trifluoromethylated dihydroisoquinolinones via visible-light-induced radical cyclization of N-allylbenzamides with CF₃SO₂Na in water at room temperature was developed. This photoinduced reaction generated the desired products in good to excellent yields under simple and mild conditions.