H2O-controlled selective thiocyanation and alkenylation of ketene dithioacetals under electrochemical oxidation

Abstract

Efficient and H₂O-controlled selective thiocyanation and alkenylation of internal olefins, to afford tetrasubstituted olefins under electrochemical oxidation, has been successfully developed. This transformation can present a critical feature wherein neither exogenous oxidants nor catalysts are required. Notably, such an electrochemical oxidation-based synthetic strategy exhibits excellent tolerance towards functional groups and can be easily scaled up with good efficiency.