Issue 4, 2019

One-step fabrication of size-controllable nicotine containing core–shell structures

Abstract

We report a one-step synthesis of nicotine-containing nanoparticles by using a size-controllable nanofiltration technique. Nanostructures with polydimethylsiloxane (PDMS) were prepared as a biocompatible well-type polymeric carrier containing a hydrophobic and highly viscous nicotine drug through a novel spontaneous emulsification solvent diffusion method. This approach could be used for efficient dispersion of nicotine in biological systems. Our present results, together with size controllability, pave a way to new types of functional material structures for novel transdermal pharmaceuticals that contain nicotine/cotinine in nanosized structures.

Graphical abstract: One-step fabrication of size-controllable nicotine containing core–shell structures

Article information

Article type
Communication
Submitted
09 Nov 2018
Accepted
01 Feb 2019
First published
04 Feb 2019
This article is Open Access
Creative Commons BY-NC license

Nanoscale Adv., 2019,1, 1305-1313

One-step fabrication of size-controllable nicotine containing core–shell structures

J. Hong, R. Guduru, S. Khizroev and L. You, Nanoscale Adv., 2019, 1, 1305 DOI: 10.1039/C8NA00335A

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements