Abinukitrine A, a unique 17,18-cyclolanostane triterpenoid from Abies nukiangensis

Yong-Li Li; Li-Jun Xue; Jie Li; Li-Ming Chen; Jian-Jun Wu; Zhuo-Ni Xu; Ying Chen; Yu-Ping Tian; Xian-Wen Yang

doi:10.1039/C8OB03117G

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Abinukitrine A, a unique 17,18-cyclolanostane triterpenoid from Abies nukiangensis†

Yong-Li Li,

*^a Li-Jun Xue,^c Jie Li,^a Li-Ming Chen,^a Jian-Jun Wu,^a Zhuo-Ni Xu,^a Ying Chen,^a Yu-Ping Tian^a and Xian-Wen Yang

*^b

Author affiliations

* Corresponding authors

^a Physical and Chemical Analysis laboratory, Division of Material Science & Quality Test, Shanghai Institute of Measurement and Testing Technology, 1500 Zhangheng Road, Shanghai 201203, China
E-mail: liyl@simt.com.cn

^b Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen 361005, China
E-mail: yangxianwen@tio.org.cn

^c Department of Medical Oncology, Jinling Hospital, Nanjing University Clinical School of Medicine, 305 East Zhongshan Road, Nanjing, China

Abstract

Abinukitrine A (1), a novel triterpenoid, was isolated from Abies nukiangensis. Comprehensive spectroscopic analysis revealed that 1 is the first example of 17,18-cyclolanostane bearing a unique 6/6/6/5/3 ring system. Its absolute configuration was unequivocally assigned by Cu-Kα X-ray single-crystallography. Compound 1 showed a potent anti-hepatitis C virus (HCV) effect.

This article is part of the themed collection: Chemical Biology in OBC

Download options Please wait...

Supplementary files

Article information

DOI: https://doi.org/10.1039/C8OB03117G
Article type: Communication
Submitted: 16 Dec 2018
Accepted: 29 Jan 2019
First published: 30 Jan 2019

Download Citation

Org. Biomol. Chem., 2019,17, 2107-2109

Permissions

Request permissions

Abinukitrine A, a unique 17,18-cyclolanostane triterpenoid from Abies nukiangensis

Y. Li, L. Xue, J. Li, L. Chen, J. Wu, Z. Xu, Y. Chen, Y. Tian and X. Yang, Org. Biomol. Chem., 2019, 17, 2107 DOI: 10.1039/C8OB03117G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Organic & Biomolecular Chemistry

Abinukitrine A, a unique 17,18-cyclolanostane triterpenoid from Abies nukiangensis†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Abinukitrine A, a unique 17,18-cyclolanostane triterpenoid from Abies nukiangensis

Social activity

Search articles by author

Spotlight

Advertisements