Glycosyl selenoacetates: versatile building blocks for the preparation of stereoselective selenoglycosides and selenium linked disaccharides†
Abstract
Glycosyl selenoacetate derivatives were prepared by the treatment of glycosyl halide with potassium selenocyanate followed by acetylation of in situ generated glycosyl selenols in one pot. A variety of selenoglycosides and selenium linked disaccharide derivatives were prepared in very good to excellent yields using glycosyl selenoacetates as stable building blocks under mild reaction conditions.
- This article is part of the themed collection: Chemical Biology in OBC