One-pot synthesis of pyranoquinolin-1-ones via Rh(iii)-catalysed redox annulation of 3-carboxyquinolines and alkynes†
Abstract
A highly efficient and simple one-pot procedure to synthesize 3,4-dihydro-pyrano[4,3-b]quinolin-1-ones via Rh(III)-catalysed [4 + 2] redox annulation of 3-carboxyquinolines with internal alkynes has been developed. This reaction features the generality of a broad scope of substrates, avoidance of external oxidants, high atom-economy and excellent regioselectivity.