Issue 16, 2019, Issue in Progress

A ratiometric fluorescent probe for detection of exogenous mitochondrial SO2 based on a FRET mechanism

Abstract

A novel imidazo[1,5-a]pyridine-hemicyanine based ratiometric fluorescent probe for detection of mitochondrial SO2 was designed and synthesized. The probe is based on a fluorescence resonance energy transfer (FRET) mechanism. It exhibits high selectivity and sensitivity towards SO32− with a fast response time (3 min) and detection limit of 0.13 μM. Further, it showed low cytotoxicity and was successfully applied to image exogenous mitochondrial SO2 in cells.

Graphical abstract: A ratiometric fluorescent probe for detection of exogenous mitochondrial SO2 based on a FRET mechanism

Supplementary files

Article information

Article type
Paper
Submitted
17 Dec 2018
Accepted
12 Mar 2019
First published
18 Mar 2019
This article is Open Access
Creative Commons BY license

RSC Adv., 2019,9, 8943-8948

A ratiometric fluorescent probe for detection of exogenous mitochondrial SO2 based on a FRET mechanism

Z. Xu, Z. Chen, A. Liu, R. Ji, X. Cao and Y. Ge, RSC Adv., 2019, 9, 8943 DOI: 10.1039/C8RA10328C

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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