Issue 65, 2019

A supramolecular hydrophobic guest transport system based on a biological macrocycle

Abstract

A protein-based macrocyclic bioactive guest loading system has been developed, which not only provides a stable 10 nm scale lipophilic environment, but also increases the solubility of potent anticancer agent SN38 in its active lactone form in aqueous medium.

Graphical abstract: A supramolecular hydrophobic guest transport system based on a biological macrocycle

Supplementary files

Article information

Article type
Paper
Submitted
15 Aug 2019
Accepted
13 Nov 2019
First published
22 Nov 2019
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2019,9, 38195-38199

A supramolecular hydrophobic guest transport system based on a biological macrocycle

Y. Ge, X. Shen, H. Cao, Y. Hao, L. Jin, J. Shang, Y. Wang, T. Pan and Z. Qi, RSC Adv., 2019, 9, 38195 DOI: 10.1039/C9RA07054K

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