Issue 70, 2019, Issue in Progress

Synthesis of rotenone loaded zein nano-formulation for plant protection against pathogenic microbes

Abstract

Rotenone (RN) is a naturally occurring isoflavone found in the root or rhizomes of fabaceae (a plant family), known for its insecticidal/pesticidal properties. Rotenone was loaded in zein nanoparticles (ZSC) by antisolvent precipitation method at room temperature. The synthesized nanoparticles showed self-assembled spherical nanostructures having 425.67 ± 7.02 and 471.33 ± 10.60 nm of hydrodynamic radii with −14.23 ± 0.21 and −17.64 ± 0.89 mV zeta potential for ZSC and RNZSC (rotenone loaded zein nanoparticles), respectively. The encapsulation of rotenone was confirmed by FTIR, 1H NMR and DSC studies. A significant encapsulation efficiency of 95.82 ± 0.038% and 5.99 ± 0.002% loading efficiency were determined by HPLC studies. Synthesized RNZSC showed excellent antimicrobial activity against plant pathogens- P. syringae and F. oxysporum. Our studies showed for the first time direct evidence of antimicrobial activity of rotenone against plant pathogens. A similar approach could be adopted for developing several new botanical based nano-formulations with their known insecticidal effect, to control certain plant diseases in an environment friendly and sustainable manner.

Graphical abstract: Synthesis of rotenone loaded zein nano-formulation for plant protection against pathogenic microbes

Supplementary files

Article information

Article type
Paper
Submitted
24 Oct 2019
Accepted
01 Dec 2019
First published
09 Dec 2019
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2019,9, 40819-40826

Synthesis of rotenone loaded zein nano-formulation for plant protection against pathogenic microbes

N. Bidyarani and U. Kumar, RSC Adv., 2019, 9, 40819 DOI: 10.1039/C9RA08739G

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