Issue 7, 2019

From enabling technologies to medicinal mechanochemistry: an eco-friendly access to hydantoin-based active pharmaceutical ingredients

Abstract

The preparation of hydantoin scaffolds using modern non-conventional activation methods is herein described. Special attention is devoted to the preparation of hydantoin-based Active Pharmaceutical Ingredients (APIs) by mechanochemistry, highlighting its advantages compared to classical solution procedures, opening new perspectives in the sustainable preparation of useful scaffolds for the pharmaceutical industry.

Graphical abstract: From enabling technologies to medicinal mechanochemistry: an eco-friendly access to hydantoin-based active pharmaceutical ingredients

Article information

Article type
Minireview
Submitted
13 Feb 2019
Accepted
28 Mar 2019
First published
28 Mar 2019

React. Chem. Eng., 2019,4, 1179-1188

From enabling technologies to medicinal mechanochemistry: an eco-friendly access to hydantoin-based active pharmaceutical ingredients

E. Colacino, A. Porcheddu, C. Charnay and F. Delogu, React. Chem. Eng., 2019, 4, 1179 DOI: 10.1039/C9RE00069K

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