Issue 30, 2019

Novel fluorene-based fluorescent probe with excellent stability for selective detection of SCN and its applications in paper-based sensing and bioimaging

Abstract

SCN is one of the most important anions in metabolic processes. However, the investigation of SCN in living systems is restricted by the lack of stable functional molecular tools. Herein, the first fluorene-based polymer fluorescent probe V1 was synthesized through rational design. Compared with small molecule fluorescent probes, V1 exhibited excellent fluorescence stability in bovine serum albumin (BSA) solution. Furthermore, the V1-based paper sensor was highly selective toward SCN in aqueous solution. Significantly, these merits of the probe V1 enable the detection of SCN in different living cell lines and zebrafish.

Graphical abstract: Novel fluorene-based fluorescent probe with excellent stability for selective detection of SCN− and its applications in paper-based sensing and bioimaging

Supplementary files

Article information

Article type
Paper
Submitted
17 Apr 2019
Accepted
20 Jun 2019
First published
21 Jun 2019

J. Mater. Chem. B, 2019,7, 4649-4654

Novel fluorene-based fluorescent probe with excellent stability for selective detection of SCN and its applications in paper-based sensing and bioimaging

T. Yang, Y. Zuo, Y. Zhang, Z. Gou, X. Wang and W. Lin, J. Mater. Chem. B, 2019, 7, 4649 DOI: 10.1039/C9TB00742C

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