Optical pico-biosensing of lead using plasmonic gold nanoparticles and a cationic peptide-based aptasensor

Manju Solra; Rajni Bala; Nishima Wangoo; Gurpreet K. Soni; Munish Kumar; Rohit K. Sharma

doi:10.1039/C9CC07407D

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Optical pico-biosensing of lead using plasmonic gold nanoparticles and a cationic peptide-based aptasensor†‡

Manju Solra,§^a Rajni Bala,§^a Nishima Wangoo,

*^b Gurpreet K. Soni,^a Munish Kumar^a and Rohit K. Sharma

*^a

Author affiliations

* Corresponding authors

^a Department of Chemistry and Centre of Advanced Studies in Chemistry, Panjab University, Sector-14, Chandigarh 160014, India
E-mail: rohitksg@pu.ac.in

^b Department of Applied Sciences, University Institute of Engineering and Technology (U.I.E.T.), Panjab University, Sector-25, Chandigarh 160014, India
E-mail: nishima@pu.ac.in

Abstract

A novel biosensor for the rapid detection of lead ions employing the optical properties of AuNPs, a lead-specific aptamer and a cationic peptide has been demonstrated. The limit of detection of the biosensor was 98.7 pM, the lowest so far obtained using colorimetry.

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Article information

DOI: https://doi.org/10.1039/C9CC07407D
Article type: Communication
Submitted: 20 Sep 2019
Accepted: 25 Nov 2019
First published: 25 Nov 2019

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Chem. Commun., 2020,56, 289-292

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Optical pico-biosensing of lead using plasmonic gold nanoparticles and a cationic peptide-based aptasensor

M. Solra, R. Bala, N. Wangoo, G. K. Soni, M. Kumar and R. K. Sharma, Chem. Commun., 2020, 56, 289 DOI: 10.1039/C9CC07407D

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Chemical Communications

Optical pico-biosensing of lead using plasmonic gold nanoparticles and a cationic peptide-based aptasensor†‡

Abstract

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Optical pico-biosensing of lead using plasmonic gold nanoparticles and a cationic peptide-based aptasensor

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