MnOx MFs as a coreaction accelerator for the construction of a novel ternary electrochemiluminescence system: ultrasensitive detection of microRNA

Rong Yang; Jia-Li Liu; Ya-Qin Chai; Ruo Yuan

doi:10.1039/C9CC08433A

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MnO_x MFs as a coreaction accelerator for the construction of a novel ternary electrochemiluminescence system: ultrasensitive detection of microRNA†

Rong Yang,^a Jia-Li Liu,

^a Ya-Qin Chai

*^a and Ruo Yuan

*^a

Author affiliations

* Corresponding authors

^a Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China
E-mail: yqchai@swu.edu.cn, yuanruo@swu.edu.cn

Abstract

By using multivalent manganese oxides microflowers (MnO_x MFs) as prominent a coreaction accelerator in luminol/dissolved oxygen system, and by combining these with DNA nanostructures for efficient immobilization of the electrochemiluminescence (ECL) quencher doxorubicin-ferrocenecarboxylic acid (Dox-FcCOOH), an ultrasensitive biosensing platform was constructed to conduct a microRNA assay in tumour cells.

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Article information

DOI: https://doi.org/10.1039/C9CC08433A
Article type: Communication
Submitted: 29 Oct 2019
Accepted: 09 Dec 2019
First published: 10 Dec 2019

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Chem. Commun., 2020,56, 976-979

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MnO_x MFs as a coreaction accelerator for the construction of a novel ternary electrochemiluminescence system: ultrasensitive detection of microRNA

R. Yang, J. Liu, Y. Chai and R. Yuan, Chem. Commun., 2020, 56, 976 DOI: 10.1039/C9CC08433A

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