Synthesis of 2-alkenylfurans via a Ag(i)-catalyzed tandem cyclization/cross-coupling reaction of enynones with iodonium ylides

Abstract

A silver(I)-catalyzed tandem cyclization/cross-coupling reaction of enynones with iodonium ylides to construct carbon–carbon double bonds has been developed. The strategy provides a novel method for the synthesis of 2-alkenylfurans. This is the first cross-coupling reaction between metal–carbene complexes and iodonium ylides.