Issue 16, 2020
From the journal:

Chemical Communications

Fluorescent nanosensor for in situ detection of phosphate and alkaline phosphatase in mice with parathyroid dysfunction†

Jiheng Xu,‡a   Hui Zhang,‡a   Wei Zhang,*a   Ping Li,a   Wen Zhang,a   Hui Wanga  and  Bo Tang ORCID logo *a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Institute of Biomedical Sciences, Shandong Normal University, Jinan 250014, P. R. China
E-mail: tangb@sdnu.edu.cn, zhangwei@sdnu.edu.cn

Abstract

A composite nanosensor based on Zr(IV)-MOFs and PNPP was developed, and was successfully applied for the in situ fluorescence imaging of phosphate and ALP levels in mice with parathyroid dysfunction. The current work provides new ideas for further development of the diagnosis of parathyroid diseases.

Graphical abstract: Fluorescent nanosensor for in situ detection of phosphate and alkaline phosphatase in mice with parathyroid dysfunction

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Article information

DOI
https://doi.org/10.1039/C9CC08828H
Article type
Communication
Submitted
12 Nov 2019
Accepted
06 Jan 2020
First published
10 Jan 2020

Chem. Commun., 2020,56, 2431-2434

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Fluorescent nanosensor for in situ detection of phosphate and alkaline phosphatase in mice with parathyroid dysfunction

J. Xu, H. Zhang, W. Zhang, P. Li, W. Zhang, H. Wang and B. Tang, Chem. Commun., 2020, 56, 2431 DOI: 10.1039/C9CC08828H

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