Cascade cycling of nicotinamide cofactor in a dual enzyme microsystem

Rui Lv; Sen Lin; Shiyong Sun; Huichao He; Fei Zheng; Daoyong Tan; Biaobiao Ma; Meng He

doi:10.1039/C9CC10031H

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Cascade cycling of nicotinamide cofactor in a dual enzyme microsystem†

Rui Lv,‡^a Sen Lin,‡^a Shiyong Sun,

*^a Huichao He,

^a Fei Zheng,^a Daoyong Tan,^a Biaobiao Ma^a and Meng He^a

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* Corresponding authors

^a School of Environment and Resource and Key Laboratory of Solid Waste Treatment and Resource Recycle of Ministry of Education, Southwest University of Science and Technology, Mianyang 621010, China
E-mail: shysun@swust.edu.cn

Abstract

Encapsulation of two enzymes, alcohol dehydrogenase (ADH) and glucose oxidase (GOx), within peroxidase-like tourmaline microparticle (TM)-based colloidosomes was used to construct a functionalized microsystem capable of sustainable cascade cycling of nicotinamide cofactor (NAD⁺/NADH) via chemical signaling between spatially confined dual-enzyme and active membranes.

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Article information

DOI: https://doi.org/10.1039/C9CC10031H
Article type: Communication
Submitted: 28 Dec 2019
Accepted: 28 Jan 2020
First published: 28 Jan 2020

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Chem. Commun., 2020,56, 2723-2726

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Cascade cycling of nicotinamide cofactor in a dual enzyme microsystem

R. Lv, S. Lin, S. Sun, H. He, F. Zheng, D. Tan, B. Ma and M. He, Chem. Commun., 2020, 56, 2723 DOI: 10.1039/C9CC10031H

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Chemical Communications

Cascade cycling of nicotinamide cofactor in a dual enzyme microsystem†

Abstract

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Cascade cycling of nicotinamide cofactor in a dual enzyme microsystem

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