Construction of a novel “ball-and-rod” MSNs-pp-PEG system: a promising antitumor drug delivery system with a particle size switchable function

Abstract

To utilize the advantages of drug carriers of different sizes, a size switchable “ball-and-rod” drug delivery system was constructed, which could switch its size in response to enzymes in tumors. It would be a promising system with long circulation and deep penetration properties, which enable its application in tumor treatment.