Issue 40, 2020
From the journal:

Chemical Communications

A novel, label-free liquid crystal biosensor for Parkinson's disease related alpha-synuclein†

Xiuxiu Yang,a   Haiyu Li,a   Xiaofang Zhao,b   Wei Liao,a   Claire Xi Zhang ORCID logo *b  and  Zhongqiang Yang ORCID logo *a  

* Corresponding authors

a Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, China
E-mail: zyang@tsinghua.edu.cn

b Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China
E-mail: clairexizhang@ccmu.edu.cn

Abstract

A liquid crystal biosensor based on DNA aptamer for sensitive detection of Parkinson's Disease (PD) related alpha-synuclein was developed. This LC biosensor is constructed using a simple and label free method, and it not only enables early PD diagnosis, but also provides a general platform for detection based on DNA aptamer.

Graphical abstract: A novel, label-free liquid crystal biosensor for Parkinson's disease related alpha-synuclein

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Article information

DOI
https://doi.org/10.1039/D0CC01025A
Article type
Communication
Submitted
08 Feb 2020
Accepted
02 Apr 2020
First published
02 Apr 2020

Chem. Commun., 2020,56, 5441-5444

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A novel, label-free liquid crystal biosensor for Parkinson's disease related alpha-synuclein

X. Yang, H. Li, X. Zhao, W. Liao, C. X. Zhang and Z. Yang, Chem. Commun., 2020, 56, 5441 DOI: 10.1039/D0CC01025A

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