Gold nanorod-assisted near-infrared light-mediated regulation of membrane ion channels activates apoptotic pathways

Juan Song; Jian-Bin Pan; Wei Zhao; Hong-Yuan Chen; Jing-Juan Xu

doi:10.1039/D0CC01858A

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Gold nanorod-assisted near-infrared light-mediated regulation of membrane ion channels activates apoptotic pathways†

Juan Song,^a Jian-Bin Pan,^a Wei Zhao,

*^a Hong-Yuan Chen^a and Jing-Juan Xu

*^a

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* Corresponding authors

^a State Key Laboratory of Analytical Chemistry for Life Science, Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China
E-mail: weizhao@nju.edu.cn, xujj@nju.edu.Cn

Abstract

We report a GNR-assisted NIR-activated tool that could open TRPV1 ion channels and regulate apoptotic protein expression, thereby inducing cell apoptosis, which might be an effective approach for cancer therapy.

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DOI: https://doi.org/10.1039/D0CC01858A
Article type: Communication
Submitted: 11 Mar 2020
Accepted: 24 Apr 2020
First published: 25 Apr 2020

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Chem. Commun., 2020,56, 6118-6121

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Gold nanorod-assisted near-infrared light-mediated regulation of membrane ion channels activates apoptotic pathways

J. Song, J. Pan, W. Zhao, H. Chen and J. Xu, Chem. Commun., 2020, 56, 6118 DOI: 10.1039/D0CC01858A

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Chemical Communications

Gold nanorod-assisted near-infrared light-mediated regulation of membrane ion channels activates apoptotic pathways†

Abstract

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Gold nanorod-assisted near-infrared light-mediated regulation of membrane ion channels activates apoptotic pathways

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