Issue 74, 2020
From the journal:

Chemical Communications

A two-photon fluorescent probe for sensitive detection and imaging of γ-glutamyl transpeptidase†

Ruijin Huo, ORCID logo ‡ab   Xiuli Zheng, ORCID logo ‡a   Weimin Liu, ORCID logo *ab   Liping Zhang,ab   Jiasheng Wu,a   Fan Li,a   Wenjun Zhang, ORCID logo c   Chun-Sing Lee ORCID logo c  and  Pengfei Wang ORCID logo *ab  

* Corresponding authors

a Key Laboratory of Photochemical Conversion and Optoelectronic Materials and City U-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China
E-mail: wmliu@mail.ipc.ac.cn, wangpf@mail.ipc.ac.cn

b School of Future Technology, University of Chinese Academy of Sciences, Beijing 100049, P. R. China

c Center Of Super-Diamond and Advanced Films (COSDAF) & Department of Materials Science and Engineering, City University of Hong Kong, Hong Kong SAR, People's Republic of China

Abstract

A GGT-activated two-photon fluorescent probe (4F-2CN–GSH) was developed based on a cascade reaction. 4F-2CN–GSH could selectivily detect GGT with low detection limit and distinguish ovarian cancer cells from normal cells using both one-photon and two-photon fluorescence imaging.

Graphical abstract: A two-photon fluorescent probe for sensitive detection and imaging of γ-glutamyl transpeptidase

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Article information

DOI
https://doi.org/10.1039/D0CC02750B
Article type
Communication
Submitted
26 Apr 2020
Accepted
04 Aug 2020
First published
05 Aug 2020

Chem. Commun., 2020,56, 10902-10905

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A two-photon fluorescent probe for sensitive detection and imaging of γ-glutamyl transpeptidase

R. Huo, X. Zheng, W. Liu, L. Zhang, J. Wu, F. Li, W. Zhang, C. Lee and P. Wang, Chem. Commun., 2020, 56, 10902 DOI: 10.1039/D0CC02750B

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