A ruthenium(II)-catalyzed selective hydrogenation of challenging primary amides and cyclic di-peptides to their corresponding primary alcohols and amino alcohols, respectively, is reported. The hydrogenation reaction operates under mild and eco-benign conditions and can be scaled-up.
M. Subaramanian, G. Sivakumar, J. K. Babu and E. Balaraman, Chem. Commun., 2020, 56, 12411 DOI: 10.1039/D0CC04550K
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