Independent bi-reversible reactions and regulable FRET efficiency achieving real-time visualization of Cys metabolizing into SO2

Tao Li; Fangjun Huo; Jianbin Chao; Caixia Yin

doi:10.1039/D0CC04839A

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Independent bi-reversible reactions and regulable FRET efficiency achieving real-time visualization of Cys metabolizing into SO₂†

Tao Li,^a Fangjun Huo,

^b Jianbin Chao

^b and Caixia Yin

*^a

Author affiliations

* Corresponding authors

^a Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China
E-mail: yincx@sxu.edu.cn

^b Research Institute of Applied Chemistry, Shanxi University, Taiyuan 030006, China

Abstract

In this work, we synthesized an independent bi-reversible reaction sensor BPC for simultaneously detecting cysteine (Cys) and sulfur dioxide (SO₂), showing multi-fluorescence signal modes due to the regulable FRET efficiency, and finally achieving real-time process visualization of Cys metabolizing into SO₂ in subcellular organelles and tumors.

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Article information

DOI: https://doi.org/10.1039/D0CC04839A
Article type: Communication
Submitted: 14 Jul 2020
Accepted: 13 Aug 2020
First published: 13 Aug 2020

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Chem. Commun., 2020,56, 11453-11456

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Independent bi-reversible reactions and regulable FRET efficiency achieving real-time visualization of Cys metabolizing into SO₂

T. Li, F. Huo, J. Chao and C. Yin, Chem. Commun., 2020, 56, 11453 DOI: 10.1039/D0CC04839A

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Chemical Communications