Issue 87, 2020
From the journal:

Chemical Communications

A biotin-guided fluorescent probe for dual-mode imaging of viscosity in cancerous cells and tumor tissues†

Mingguang Ren, ORCID logo *a   Qingyu Xu,a   Shoujuan Wang,a   Lu Liub  and  Fangong Kong*a  

* Corresponding authors

a State Key Laboratory of Biobased Material and Green Papermaking, Key Laboratory of Pulp & Paper Science and Technology of Shandong Province/Ministry of Education, Shandong Academy of Sciences, Qilu University of Technology, Jinan 250353, China
E-mail: rmg888@163.com, kfgwsj1566@163.com

b Shandong Management University, Jinan, Shandong, China

Abstract

A cancer cell targeted fluorescent viscosity probe has been designed and synthesized to specifically visualise viscosity changes in biotin receptor (BiR) positive cells over biotin negative cells via dual-mode fluorescence imaging: fluorescence intensity mode and fluorescence lifetime mode.

Graphical abstract: A biotin-guided fluorescent probe for dual-mode imaging of viscosity in cancerous cells and tumor tissues

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Article information

DOI
https://doi.org/10.1039/D0CC05039C
Article type
Communication
Submitted
23 Jul 2020
Accepted
29 Sep 2020
First published
30 Sep 2020

Chem. Commun., 2020,56, 13351-13354

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A biotin-guided fluorescent probe for dual-mode imaging of viscosity in cancerous cells and tumor tissues

M. Ren, Q. Xu, S. Wang, L. Liu and F. Kong, Chem. Commun., 2020, 56, 13351 DOI: 10.1039/D0CC05039C

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