Issue 82, 2020
From the journal:

Chemical Communications

Circularized blocker-displacement amplification for multiplex detection of rare DNA variants†

Wei Lai,a   Mingshu Xiao,a   Haihong Yang,a   Li Li, ORCID logo a   Chunhai Fanb  and  Hao Pei ORCID logo *a  

* Corresponding authors

a Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, Shanghai, P. R. China
E-mail: peihao@chem.ecnu.edu.cn

b School of Chemistry and Chemical Engineering, and Institute of Molecular Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China

Abstract

A superselective isothermal amplification technique, termed circularized blocker-displacement amplification, was developed for multiplex analysis of rare DNA variants.

Graphical abstract: Circularized blocker-displacement amplification for multiplex detection of rare DNA variants

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Article information

DOI
https://doi.org/10.1039/D0CC05283C
Article type
Communication
Submitted
04 Aug 2020
Accepted
14 Sep 2020
First published
15 Sep 2020

Chem. Commun., 2020,56, 12331-12334

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Circularized blocker-displacement amplification for multiplex detection of rare DNA variants

W. Lai, M. Xiao, H. Yang, L. Li, C. Fan and H. Pei, Chem. Commun., 2020, 56, 12331 DOI: 10.1039/D0CC05283C

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