Cobalt-catalyzed carboxylation of aryl and vinyl chlorides with CO2

Abstract

The transition-metal-catalyzed carboxylation of aryl and vinyl chlorides with CO₂ is rarely studied, and has been achieved only with a Ni catalyst or combination of palladium and photoredox. In this work, the cobalt-catalyzed carboxylation of aryl and vinyl chlorides and bromides with CO₂ has been developed. These transformations proceed under mild conditions and exhibit a broad substrate scope, affording the corresponding carboxylic acids in good to high yields.