Novel phthalocyanine-based micelles/PNIPAM composite hydrogels: spatially/temporally controlled drug release triggered by NIR laser irradiation†
Abstract
Near-infrared (NIR) light-responsive hydrogels hold significant potential for biomedical application, especially in the remote-controlled release of anticancer drugs. Herein, we report a novel NIR light responsive composite hydrogel system that undergoes structural changes to realize drug delivery and precise release, which is constructed by a poly(N-isopropylacrylamide) network and a photothermal agent, 4OCSPC/F127 micelles.