Regioselective hydroarylation and arylation of maleimides with indazoles via a Rh(iii)-catalyzed C–H activation

Abstract

Switchable Rh(III)-catalyzed highly regioselective hydroarylation and oxidative arylation of maleimides with 2-arylindazoles via C–H activation have been demonstrated. The reaction affords 3-(2-(2H-indazol-2-yl)phenyl)succinimide and 3-(2-(2H-indazol-2-yl)phenyl)maleimide derivatives in high yields with wide functional group tolerance. A mechanistic study was performed to depict C–H bond cleavage that might be involved in the turnover limiting step.