Tracking down the brominated single electron oxidants in recent organic red-ox transformations: photolysis and photocatalysis

Abstract

A wide range of organic and inorganic brominated compounds including molecular bromine have been extensively used as oxidants in many organic photo-redox transformations in recent years, an area of ever growing interest because of greener and milder approaches. The oxidation power of these compounds is utilized through both mechanistic pathways (by hydrogen atom transfer or HAT in the absence of a photocatalyst and a combination of single electron transfer or SET and/or HAT in the presence of a photocatalyst). Not only as terminal oxidants for regeneration of photocatalysts, but brominated reactants have also contributed to the oxidation of the reaction intermediate(s) to carry on the radical chain process in several reactions. Here in this review mainly the non-brominative oxidative product formations are discussed, carried out since the last two decades, skipping the instances where they acted as terminal oxidants only to regenerate photocatalysts. The reactions are used to generate natural products, pharmaceuticals and beyond.