Issue 17, 2020
From the journal:

Organic Chemistry Frontiers

Iron catalyzed ketoalkylation and ketoalkylation/etherification of styrenes initiated by selective C–C bond cleavage†

Meng-Ting Suo,a   Shuo Yang,a   Jun-Cheng Yang,a   Ze-Yu Liu,a   Jun-Jie Zhanga  and  Li-Na Guo ORCID logo *a  

* Corresponding authors

a Department of Chemistry, School of Chemistry, Xi'an Key Laboratory of Sustainable Energy Material Chemistry, and MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, Xi'an Jiaotong University, Xi'an 710049, China
E-mail: guoln81@xjtu.edu.cn

Abstract

An iron-catalyzed ketoalkyl-Heck-type coupling initiated by radical C–C bond cleavage is described. The features of this protocol include mild conditions (40 °C, free of ligands and bases), broad substrate scope, excellent functional group tolerance and stereoselectivity. Satisfactorily, this Fe-based catalytic system was also applicable for the three-component ketoalkylation/etherification of styrenes.

Graphical abstract: Iron catalyzed ketoalkylation and ketoalkylation/etherification of styrenes initiated by selective C–C bond cleavage

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D0QO00671H
Article type
Research Article
Submitted
05 Jun 2020
Accepted
11 Jul 2020
First published
15 Jul 2020

Org. Chem. Front., 2020,7, 2414-2418

Permissions

Request permissions

Iron catalyzed ketoalkylation and ketoalkylation/etherification of styrenes initiated by selective C–C bond cleavage

M. Suo, S. Yang, J. Yang, Z. Liu, J. Zhang and L. Guo, Org. Chem. Front., 2020, 7, 2414 DOI: 10.1039/D0QO00671H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements