Palladium-catalyzed double-carbonylative cyclization of propargyl alcohols and aryl triflates to expedite construction of 4-aroyl-furan-2(5H)-ones†
Abstract
A palladium-catalyzed double-carbonylative cyclization of propargyl alcohols and aryl triflates has been developed. Various 4-aroyl-furan-2(5H)-one scaffolds were produced in good yields with Cr(CO)6 as the CO source. Control experiments were performed as well, and a reasonable reaction mechanism was proposed.