Issue 3, 2020

Synthesis and characterization of tannic acid–PEG hydrogel via Mitsunobu polymerization

Abstract

Tannic acid (TA) based materials have received significant interest owing to their broad spectrum of chemical and biological properties. Herein, a novel tannic acid based hydrogel, TA–PEG hydrogel, was synthesized via Mitsunobu polymerization/polycondensation, in which TA and polyethylene glycol (PEG) were simply crosslinked together by ether linkages. This method was performed in one pot, straightforward, metal free and robust, ignoring the strong ionic/hydrophobic interactions between tannic acid and PEG. Bearing catechol and pyrogallol units from TA, TA–PEG hydrogel did not only reduce the silver and gold precursor, but also served as a capping agent and stabilizer for the in situ formed Au and Ag nanoparticles (NPs). Furthermore, the antioxidant activity of the hydrogel was excellent (94%) in the case of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging. TA–PEG hydrogel also showed antibacterial activity against Staphylococcus aureus and Escherichia coli. This work suggested a new method leading to polyphenol based soft materials rather than a complex coacervated microstructure. The resulting TA–PEG hydrogel has potential application in biomedical materials.

Graphical abstract: Synthesis and characterization of tannic acid–PEG hydrogel via Mitsunobu polymerization

Supplementary files

Article information

Article type
Paper
Submitted
07 Nov 2019
Accepted
18 Dec 2019
First published
09 Jan 2020
This article is Open Access
Creative Commons BY license

RSC Adv., 2020,10, 1724-1732

Synthesis and characterization of tannic acid–PEG hydrogel via Mitsunobu polymerization

C. Chen, X. Geng, Y. Pan, Y. Ma, Y. Ma, S. Gao and X. Huang, RSC Adv., 2020, 10, 1724 DOI: 10.1039/C9RA09229C

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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