Recyclable anhydride catalyst for H2O2 oxidation: N-oxidation of pyridine derivatives

Abstract

The catalytic efficiency and recyclability of poly(maleic anhydride-alt-1-octadecene) (Od-MA) and poly(maleic anhydride-alt-1-isobutylene) (Bu-MA) were evaluated for use in the development of a metal-free, reusable catalyst for the oxidation of pyridines to pyridine N-oxides in the presence of H₂O₂. The Od-MA catalyst was easily recovered via filtration with recovery yields exceeding 99.8%. The catalyst retained its activity after multiple uses and did not require any treatment for reuse. The Od-MA and H₂O₂ catalytic system described herein is eco-friendly, operationally simple, and cost-effective; thus, it is industrially applicable. Od-MA and H₂O₂ could potentially be used in place of percarboxylic acid as an oxidant in a wide range of oxidation reactions.