Issue 40, 2020

Removal of the A10 adenosine in a DNA-stabilized Ag16 nanocluster

Abstract

The role of the terminal adenosine (A10) on the spectroscopic and structural properties of a previously described DNA-stabilized Ag16 nanocluster (DNA:Ag16NC) is presented. In the original DNA:Ag16NCs (5′-CACCTAGCGA-3′), the A10 nucleobase was involved in an Ag+-mediated interaction with an A10 in a neighboring asymmetric unit, and did not interact with the Ag16NC. Therefore, we synthesized AgNCs embedded in the corresponding 9-base sequence in order to investigate the crystal structure of these new DNA-A10:Ag16NCs and analyze the photophysical properties of the solution and crystalline state. The X-ray crystallography and spectroscopic measurements revealed that the 3′-end adenosine has little importance with respect to the photophysics and structure of the Ag16NCs. Additionally, the new crystallographic data was recorded with higher spatial resolution leading to a more detailed insight in the interactions between the nucleotides and Ag atoms.

Graphical abstract: Removal of the A10 adenosine in a DNA-stabilized Ag16 nanocluster

Supplementary files

Article information

Article type
Paper
Submitted
23 Mar 2020
Accepted
13 Jun 2020
First published
23 Jun 2020
This article is Open Access
Creative Commons BY license

RSC Adv., 2020,10, 23854-23860

Removal of the A10 adenosine in a DNA-stabilized Ag16 nanocluster

C. Cerretani, J. Kondo and T. Vosch, RSC Adv., 2020, 10, 23854 DOI: 10.1039/D0RA02672G

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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