Reply to the ‘Comment on “Physicochemical stimuli as tuning parameters to modulate the structure and stability of nanostructured lipid carriers and release kinetics of encapsulated antileprosy drugs”’ by J. Kang and A. M. Kang, J. Mater. Chem. B, 2020, 8, DOI: 10.1039/D0TB01160F

Abstract

In a recent comment [J. Kang and A. M. Kang, J. Mater. Chem. B, 2020, 8, DOI: 10.1039/D0TB01160F] on our article [R. Kanwar, M. Gradzielski, S. Prevost, G. Kaur, M. S. Appavou and S. K. Mehta, J. Mater. Chem. B., 2019, 7, 6539], the authors tried to demonstrate that the binding phenomenon between drug-loaded nanostructured lipid carriers and the protein BSA was subjected to enthalpy–entropy compensation, rather than being entropy-driven. The outcome, however, remains the same in spite of the complicated analysis attempted. While we appreciate their effort to extract more information from our data, we have a number of remarks on their process.