Ni/Fe layered double hydroxide nanosheet/G-quadruplex as a new complex DNAzyme with highly enhanced peroxidase-mimic activity

Yao Yao; Mingliang Xue; Wei Mao; Yana Li; Anni Zhu; Tianyu Chen; Wei Shen; Chang Liu; Lizhuang Chen; Sheng Tang

doi:10.1039/D1AN01405F

Ni/Fe layered double hydroxide nanosheet/G-quadruplex as a new complex DNAzyme with highly enhanced peroxidase-mimic activity†

Yao Yao,^a Mingliang Xue,^a Wei Mao,^a Yana Li,^a Anni Zhu,^a Tianyu Chen,^a Wei Shen,

*^a Chang Liu,

*^b Lizhuang Chen

^a and Sheng Tang

*^a

Author affiliations

* Corresponding authors

^a School of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003, Jiangsu Province, PR China
E-mail: shenweivv@126.com, tangsheng.nju@gmail.com

^b School of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang 212003, Jiangsu Province, PR China
E-mail: liuchang01890@just.edu.cn

Abstract

A novel and low-cost DNAzyme, Ni/Fe layered double hydroxide (LDH) nanosheet/G-quadruplex (without hemin) with enhanced peroxidase-mimic activity was designed. The catalytic mechanism was investigated. The detection of Cu(II) in actual serum samples could be realized sensitively via this efficient DNAzyme-based method.

Analyst

Ni/Fe layered double hydroxide nanosheet/G-quadruplex as a new complex DNAzyme with highly enhanced peroxidase-mimic activity†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Ni/Fe layered double hydroxide nanosheet/G-quadruplex as a new complex DNAzyme with highly enhanced peroxidase-mimic activity

Social activity

Search articles by author

Spotlight

Advertisements