Issue 12, 2021

A ratiometric fluorescent probe for monitoring pH fluctuations during autophagy in living cells

Abstract

We present a ratiometric fluorescent probe for monitoring pH featuring superb photostability and chemostability. The down-regulation of the intracellular pH during autophagy in living cells induced by various stimuli, including several drugs and starvation, was quantified, which could provide instructive value to construct autophagy models to study the related pathological processes.

Graphical abstract: A ratiometric fluorescent probe for monitoring pH fluctuations during autophagy in living cells

Supplementary files

Article information

Article type
Communication
Submitted
28 Nov 2020
Accepted
03 Jan 2021
First published
04 Jan 2021

Chem. Commun., 2021,57, 1510-1513

A ratiometric fluorescent probe for monitoring pH fluctuations during autophagy in living cells

S. Wang, B. Wang, L. Zhu, J. Hou and K. Yu, Chem. Commun., 2021, 57, 1510 DOI: 10.1039/D0CC07788G

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