Issue 36, 2021
From the journal:

Chemical Communications

Ruthenium(ii) complexes as bioorthogonal two-photon photosensitizers for tumour-specific photodynamic therapy against triple-negative breast cancer cells†

Mingwei Lin,a   Shanshan Zou,a   Xinxing Liao,a   Yu Chen, ORCID logo *a   Diqing Luo,*b   Liangnian Jia  and  Hui Chao ORCID logo *a  

* Corresponding authors

a MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, P. R. China
E-mail: ceschh@mail.sysu.edu.cn, chenyu63@mail.sysu.edu.cn

b Department of Dermatology, The Eastern Division of the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, P. R. China
E-mail: luodq@mail.sysu.edu.cn

Abstract

Herein, we developed the first Ru(II) complex-based bioorthogonal two-photon photosensitizers. Through bioorthogonal labelling, they realize effective tumour-specific photodynamic therapy against triple-negative breast cancer cells.

Graphical abstract: Ruthenium(ii) complexes as bioorthogonal two-photon photosensitizers for tumour-specific photodynamic therapy against triple-negative breast cancer cells

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Article information

DOI
https://doi.org/10.1039/D1CC00661D
Article type
Communication
Submitted
04 Feb 2021
Accepted
23 Mar 2021
First published
27 Mar 2021

Chem. Commun., 2021,57, 4408-4411

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Ruthenium(II) complexes as bioorthogonal two-photon photosensitizers for tumour-specific photodynamic therapy against triple-negative breast cancer cells

M. Lin, S. Zou, X. Liao, Y. Chen, D. Luo, L. Ji and H. Chao, Chem. Commun., 2021, 57, 4408 DOI: 10.1039/D1CC00661D

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