Issue 64, 2021

Biomimetic calcium-inactivated ion/molecular channel

Abstract

A phosphopeptide-modified nanochannel was prepared based on a conical polymeric nanopore. It shows a reversible Ca2+-induced inactivation effect toward the ion flow and molecular transport, resulting from Ca2+ binding-caused surface charge neutralization and hydrophilicity reduction, and Ca2+ removal by the competitive binding.

Graphical abstract: Biomimetic calcium-inactivated ion/molecular channel

Supplementary files

Article information

Article type
Communication
Submitted
10 Jun 2021
Accepted
14 Jul 2021
First published
14 Jul 2021

Chem. Commun., 2021,57, 7914-7917

Biomimetic calcium-inactivated ion/molecular channel

M. Li, Y. Cao, X. Zhang, D. Wang, S. Qian, G. Li, F. Zhang, Y. Xiong and G. Qing, Chem. Commun., 2021, 57, 7914 DOI: 10.1039/D1CC03058B

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