Issue 82, 2021
From the journal:

Chemical Communications

“Covalent biosensing” enables a one-step, reagent-less, low-cost and highly robust assay of SARS-CoV-2†

Kai Zhang, ORCID logo ‡ab   Jinlong Li,‡c   Zhenqiang Fan, ORCID logo a   Hao Li*d  and  Jing-Juan Xu ORCID logo *b  

* Corresponding authors

a NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu 214063, China

b State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China
E-mail: xujj@nju.edu.cn

c Department of Laboratory Medicine, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing 210003, P. R. China

d School of Biological Science and Technology, University of Jinan, No. 106 Jiwei Road, Jinan, Shandong 250022, China
E-mail: cardely@126.com

Abstract

We have established a new protocol for detecting severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) using a peptidomimetic to covalently detect a viral marker protease.

Graphical abstract: “Covalent biosensing” enables a one-step, reagent-less, low-cost and highly robust assay of SARS-CoV-2

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Article information

DOI
https://doi.org/10.1039/D1CC03686F
Article type
Communication
Submitted
09 Jul 2021
Accepted
11 Sep 2021
First published
22 Sep 2021

Chem. Commun., 2021,57, 10771-10774

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“Covalent biosensing” enables a one-step, reagent-less, low-cost and highly robust assay of SARS-CoV-2

K. Zhang, J. Li, Z. Fan, H. Li and J. Xu, Chem. Commun., 2021, 57, 10771 DOI: 10.1039/D1CC03686F

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