Issue 90, 2021
From the journal:

Chemical Communications

A–DA′D–A fused-ring small molecule-based nanoparticles for combined photothermal and photodynamic therapy of cancer†

Bing Lu, ORCID logo *a   Zhecheng Zhang,a   Danni Jin,a   Xiaolei Yuan, ORCID logo a   Jin Wang,a   Yue Ding, ORCID logo a   Yang Wang ORCID logo a  and  Yong Yao ORCID logo *a  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Nantong University, Nantong, Jiangsu, P. R. China
E-mail: 2020028lubing@ntu.edu.cn

Abstract

New nanoparticles (Y6 NPs) based on the A–DA′D–A fused-ring conjugated small molecule Y6 have been prepared for the combined photothermal and photodynamic therapy of cancer. Y6 NPs show excellent light absorption from 300 to 900 nm, a good photothermal conversion efficiency of 57% and reactive oxygen species generation capability. The high photothermal conversion ability and superior photodynamic activity of Y6 NPs endow them with great potential for cancer therapy.

Graphical abstract: A–DA′D–A fused-ring small molecule-based nanoparticles for combined photothermal and photodynamic therapy of cancer

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Article information

DOI
https://doi.org/10.1039/D1CC04629B
Article type
Communication
Submitted
20 Aug 2021
Accepted
15 Oct 2021
First published
15 Oct 2021

Chem. Commun., 2021,57, 12020-12023

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A–DA′D–A fused-ring small molecule-based nanoparticles for combined photothermal and photodynamic therapy of cancer

B. Lu, Z. Zhang, D. Jin, X. Yuan, J. Wang, Y. Ding, Y. Wang and Y. Yao, Chem. Commun., 2021, 57, 12020 DOI: 10.1039/D1CC04629B

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