Role of the ancillary ligand in controlling the lysozyme affinity and electronic properties of terpyridine fac-Re(CO)3 complexes

Abstract

The lysozyme binding affinity and the electronic properties of [ReX(CO)₃(terpy-κ²N¹,N²)] (X = Br⁻ and triazolate^{COOCH₂CH₃,CF₃}) were reported. The triazolate complex was prepared in a [3 + 2] cycloaddition click reaction. The bromo compound reacted with lysozyme affording adducts with Re(CO)₃⁺ fragments, while the triazolate compound persisted. A red shift of the MLCT band of the triazolate compound in progressively less polar solvents may be due to the negative solvatochromism.