Issue 9, 2021

Laser synthesis: a solvent-free approach for the preparation of phenylthiazolo[5,4-b]pyridine derivatives

Abstract

We describe here a rapid and straightforward solvent-free method to access phenylthiazolo[5,4-b]pyridines using a Nd-YAG laser NANO-NY81-10 (λ = 355 nm, 10 Hz pulse frequency; 8 ns pulse duration). This newly presented method successfully brings several improvements to the laser assisted synthesis of N,S-heterocycles. We are able to provide a solvent-, metal- and base-free method with good yield and a substantial reduction in reaction time.

Graphical abstract: Laser synthesis: a solvent-free approach for the preparation of phenylthiazolo[5,4-b]pyridine derivatives

Supplementary files

Article information

Article type
Paper
Submitted
30 Nov 2020
Accepted
21 Jan 2021
First published
27 Jan 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 5003-5007

Laser synthesis: a solvent-free approach for the preparation of phenylthiazolo[5,4-b]pyridine derivatives

R. Jemili, J. F. Campos, N. Dumuis, H. Rabat, N. Semmar and S. Berteina-Raboin, RSC Adv., 2021, 11, 5003 DOI: 10.1039/D0RA10094C

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