Issue 32, 2021
From the journal:

RSC Advances

Solvent-free synthesis of propargylamines: an overview

Ravi Manujyothi,a   Thaipparambil Aneejab  and  Gopinathan Anilkumar ORCID logo *abc  

* Corresponding authors

a Institute for Integrated Programmes and Research in Basic Sciences (IIRBS), Mahatma Gandhi University, Priyadarsini Hills P O, Kottayam, Kerala, 686560 India
E-mail: anilgi1@yahoo.com, anil@mgu.ac.in
Fax: +91-481-2731036

b School of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P O, Kottayam, Kerala, 686560 India

c Advanced Molecular Materials Research Centre (AMMRC), Mahatma Gandhi University, Priyadarsini Hills P O, Kottayam, Kerala, 686560 India

Abstract

Propargylamines are a class of compounds with many pharmaceutical and biological properties. A green approach to synthesize such compounds is very relevant. This review aims to describe the solvent-free synthetic approaches towards propargylamines via A3 and KA2 coupling reactions covering the literature up to 2021.

Graphical abstract: Solvent-free synthesis of propargylamines: an overview

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Article information

DOI
https://doi.org/10.1039/D1RA03324G
Article type
Review Article
Submitted
28 Apr 2021
Accepted
25 May 2021
First published
30 May 2021
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2021,11, 19433-19449

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Solvent-free synthesis of propargylamines: an overview

R. Manujyothi, T. Aneeja and G. Anilkumar, RSC Adv., 2021, 11, 19433 DOI: 10.1039/D1RA03324G

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