Issue 21, 2022

Semi-quantification of the binding constant based on bond breaking in a combined acoustic–gravitational field

Abstract

In this study, we propose a semi-quantification method based on breaking bonds between microparticles and glass plates in a combined acoustic–gravitational field. The semi-quantified binding constant values for BSA–ibuprofen, BSA–ciprofloxacin, ConA–glycogen, ConA–mannan, and BSA–naproxen calculated using this method were 7.5 × 103, 1.6 × 104, 2.3 × 105, 2.4 × 106 and 9.0 × 107 M−1, respectively, which were in concord with the reported values.

Graphical abstract: Semi-quantification of the binding constant based on bond breaking in a combined acoustic–gravitational field

Supplementary files

Article information

Article type
Communication
Submitted
13 Jun 2022
Accepted
21 Sep 2022
First published
21 Sep 2022

Analyst, 2022,147, 4735-4738

Semi-quantification of the binding constant based on bond breaking in a combined acoustic–gravitational field

A. Miyagawa, K. Oshiyama, S. Nagatomo and K. Nakatani, Analyst, 2022, 147, 4735 DOI: 10.1039/D2AN00977C

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