Issue 18, 2022
From the journal:

Analyst

Combination of the lateral-flow immunoassay with multicolor gold nanorod etching for the semi-quantitative detection of digoxin†

Daniel W. Bradbury, ORCID logo ‡a   Jasmine T. Trinh,‡a   Milo J. Ryan,‡a   Kyle J. Chen, ORCID logo a   Adel A. Battikha, ORCID logo a   Benjamin M. Wuab  and  Daniel T. Kamei ORCID logo *a  

* Corresponding authors

a Department of Bioengineering, University of California, Los Angeles, CA 90095, USA
E-mail: kamei@seas.ucla.edu

b Division of Advanced Prosthodontics & Weintraub Center for Reconstructive Biotechnology, School of Dentistry, University of California, Los Angeles, CA 90095, USA

Abstract

We are the first to combine the lateral-flow immunoassay (LFA) with gold nanorod (GNR) etching to achieve a multicolor readout where the color produced was correlated with digoxin concentrations in human serum in the relevant range for therapeutic drug monitoring of 0.5–3.0 ng mL−1.

Graphical abstract: Combination of the lateral-flow immunoassay with multicolor gold nanorod etching for the semi-quantitative detection of digoxin

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Article information

DOI
https://doi.org/10.1039/D2AN01047J
Article type
Communication
Submitted
28 Jun 2022
Accepted
15 Aug 2022
First published
17 Aug 2022

Analyst, 2022,147, 4000-4007

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Combination of the lateral-flow immunoassay with multicolor gold nanorod etching for the semi-quantitative detection of digoxin

D. W. Bradbury, J. T. Trinh, M. J. Ryan, K. J. Chen, A. A. Battikha, B. M. Wu and D. T. Kamei, Analyst, 2022, 147, 4000 DOI: 10.1039/D2AN01047J

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