Issue 1, 2022

A lysosomal targeted fluorescent probe based on coumarin for monitoring hydrazine in living cells with high performance

Abstract

A lysosomal targeted fluorescent probe based on coumarin for monitoring hydrazine (N2H4) in living cells was designed and synthesised. The novel fluorescent probe Cou-Lyso-N2H4, in response to N2H4, exhibited good selectivity, low cytotoxicity, and lysosomal localization, which could be suitable for studying the harmfulness of N2H4 in subcellular organelles during various physiological processes.

Graphical abstract: A lysosomal targeted fluorescent probe based on coumarin for monitoring hydrazine in living cells with high performance

Supplementary files

Article information

Article type
Communication
Submitted
27 Oct 2021
Accepted
23 Nov 2021
First published
23 Nov 2021

Anal. Methods, 2022,14, 17-21

A lysosomal targeted fluorescent probe based on coumarin for monitoring hydrazine in living cells with high performance

J. Jiang, Z. Zhang, J. Qu and J. Wang, Anal. Methods, 2022, 14, 17 DOI: 10.1039/D1AY01821C

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